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1

High-grade glioma mouse models and their applicability for preclinical testing

Nienke A. de Vries, Jos H. Beijnen, Olaf van Tellingen

Journal:

Cancer Treatment Reviews

Year:

2009

Language:

english

File:

PDF, 337 KB

english, 2009

2

Normal Viability and Altered Pharmacokinetics in Mice Lacking mdr1-Type (Drug-Transporting) P-Glycoproteins

Alfred H. Schinkel, Ulrich Mayer, Els Wagenaar, Carla A. A. M. Mol, Liesbeth Van Deemter, Jaap J. M. Smit, Martin A. Van Der Valk, Arie C. Voordouw, Hergen Spits, Olaf Van Tellingen, J. Mark J. M. Zij

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.55 MB

english, 1997

3

Mps1 inhibitors synergise with low doses of taxanes in promoting tumour cell death by enhancement of errors in cell division

Maia, Ana Rita R., Linder, Simon, Song, Ji-Ying, Vaarting, Chantal, Boon, Ute, Pritchard, Colin E. J., Velds, Arno, Huijbers, Ivo J., van Tellingen, Olaf, Jonkers, Jos, Medema, René H.

Journal:

British Journal of Cancer

Year:

2018

Language:

english

File:

PDF, 2.42 MB

english, 2018

4

Determination of imatinib mesylate and its main metabolite (CGP74588) in human plasma and murine specimens by ion-pairing reversed-phase high-performance liquid chromatography

Roos L. Oostendorp, Jos H. Beijnen, Jan H. M. Schellens, Olaf van Tellingen

Journal:

Biomedical Chromatography

Year:

2007

Language:

english

File:

PDF, 319 KB

english, 2007

5

Determination of topotecan in human and mouse plasma and in mouse tissue homogenates by reversed-phase high-performance liquid chromatography

Nienke A. de Vries, Mariët Ouwehand, Tessa Buckle, Jos H. Beijnen, Olaf van Tellingen

Journal:

Biomedical Chromatography

Year:

2007

Language:

english

File:

PDF, 412 KB

english, 2007

6

MRP2 (ABCC2) transports taxanes and confers paclitaxel resistance and both processes are stimulated by probenecid

Maarten T. Huisman, Aniska A. Chhatta, Olaf van Tellingen, Jos H. Beijnen, Alfred H. Schinkel

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 115 KB

english, 2005

7

Magnetic resonance imaging-based detection of glial brain tumors in mice after antiangiogenic treatment

An Claes, Giulio Gambarota, Bob Hamans, Olaf van Tellingen, Pieter Wesseling, Cathy Maass, Arend Heerschap, William Leenders

Journal:

International Journal of Cancer

Year:

2008

Language:

english

File:

PDF, 301 KB

english, 2008

8

Tumor microvasculature supports proliferation and expansion of glioma-propagating cells

Tijana Borovski, Joost J.C. Verhoeff, Rosemarie ten Cate, Kate Cameron, Nienke A. de Vries, Olaf van Tellingen, Dirk J. Richel, Wouter R. van Furth, Jan Paul Medema, Martin R. Sprick

Journal:

International Journal of Cancer

Year:

2009

Language:

english

File:

PDF, 547 KB

english, 2009

9

Fully automated high-performance liquid chromatographic method for the determination of carzelesin (U-80,244) and metabolites (U-76,073 and U-76,074) in human plasma

Olaf van Tellingen, Esther M. Pels, Roland E.C. Henrar, Lawrence J. Schaaf, Guy E. Padbury, Jos H. Beijnen, Willem J. Nooijen

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1994

Language:

english

File:

PDF, 414 KB

english, 1994

10

Determination of paclitaxel and metabolites in mouse plasma, tissues, urine and faeces by semi-automated reversed-phase high-performance liquid chromatography

Alexander Sparreboom, Olaf van Tellingen, Willem J. Noojien, Jos H. Beijnen

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1995

Language:

english

File:

PDF, 605 KB

english, 1995

11

Determination of polyoxyethyleneglycerol triricinoleate 35 (Cremophor EL) in plasma by pre-column derivatization and reversed-phase high-performance liquid chromatography

Alex Sparreboom, Olaf van Tellingen, Manon T. Huizing, Willem J. Nooijen, Jos H. Beijnen

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1996

Language:

english

File:

PDF, 467 KB

english, 1996

12

Analytical methods for the determination of vinca alkaloids in biological specimens: A survey of the literature

Olaf van Tellingen, Jos H. Beijnen, Willem J. Nooyen

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

1991

Language:

english

File:

PDF, 412 KB

english, 1991

13

Development and validation of a method to determine the unbound paclitaxel fraction in human plasma

H.J.G. Desirée van den Bongard, E. Marleen Kemper, Olaf van Tellingen, Hilde Rosing, Ron A.A. Mathôt, Jan H.M. Schellens, Jos H. Beijnen

Journal:

Analytical Biochemistry

Year:

2004

Language:

english

File:

PDF, 155 KB

english, 2004

14

Simultaneous determination of AZD1152 (prodrug) and AZD1152-hydroxyquinazoline pyrazol anilide by reversed phase liquid chromatography

Dick Pluim, Jos H. Beijnen, Jan H.M. Schellens, Olaf van Tellingen

Journal:

Journal of Chromatography B

Year:

2009

Language:

english

File:

PDF, 255 KB

english, 2009

15

Determination of cyclosporin A in human and mouse plasma by reversed-phase high-performance liquid chromatography

Heleen A. Bardelmeijer, Mariët Ouwehand, Jos H. Beijnen, Jan H.M. Schellens, Olaf van Tellingen

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

2001

Language:

english

File:

PDF, 80 KB

english, 2001

16

Determination of doxorubicin and metabolites in murine specimens by high-performance liquid chromatography

Judith van Asperen, Olaf van Tellingen, Jos H Beijnen

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1998

Language:

english

File:

PDF, 134 KB

english, 1998

17

High-performance liquid chromatographic bio-analysis of PSC 833 in human and murine plasma

Olaf van Tellingen, Marleen Kemper, Frank Tijssen, Judith van Asperen, Willem J. Nooijen, Jos H. Beijnen

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1998

Language:

english

File:

PDF, 95 KB

english, 1998

18

Bioanalysis of aplidine, a new marine antitumoral depsipeptide, in plasma by high-performance liquid chromatography after derivatization with trans-4′-hydrazino-2-stilbazole

Rolf W Sparidans, J.Jantien Kettenes-van den Bosch, Olaf van Tellingen, Bastiaan Nuyen, Roland E.C Henrar, José M Jimeno, Glynn Faircloth, Pablo Floriano, Kenneth L Rinehart, Jos H Beijnen

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1999

Language:

english

File:

PDF, 222 KB

english, 1999

19

Bioanalysis and pharmacokinetics of (investigational) vinca alkaloids

Olaf van Tellingen

Journal:

International Journal of Clinical Pharmacy

Year:

1994

Language:

english

File:

PDF, 416 KB

english, 1994

20

Entrapment by Cremophor EL decreases the absorption of paclitaxel from the gut

Heleen A. Bardelmeijer, Mariët Ouwehand, Mirte M. Malingré, Jan H. Schellens, Jos H. Beijnen, Olaf van Tellingen

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2002

Language:

english

File:

PDF, 124 KB

english, 2002

21

Metabolism of docetaxel in mice

Heleen A. Bardelmeijer, Arjan B. G. H. Roelofs, Michel J. X. Hillebrand, Jos H. Beijnen, Jan H. M. Schellens, Olaf van Tellingen

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2005

Language:

english

File:

PDF, 307 KB

english, 2005

22

The effect of P-glycoprotein and cytochrome P450 3a on the oral bioavailability of vinorelbine in mice

Rogier R. Press, Tessa Buckle, Jos H. Beijnen, Olaf van Tellingen

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2006

Language:

english

File:

PDF, 285 KB

english, 2006

23

A phase I and pharmacokinetic study of bi-daily dosing of oral paclitaxel in combination with cyclosporin A

Mirte M. Malingré, Jos H. Beijnen, Hilde Rosing, Franciska J. Koopman, Olaf van Tellingen, Ken Duchin, Wim W. Ten Bokkel Huinink, Martha Swart, Jan Lieverst, Jan H.M. Schellens

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2001

Language:

english

File:

PDF, 114 KB

english, 2001

24

The vascular compartment hampers accurate determination of teniposide penetration into brain tumor tissue

Olaf van Tellingen, Willem Boogerd, Willem J. Nooijen, Jos H. Beijnen

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1997

Language:

english

File:

PDF, 142 KB

english, 1997

25

Differential effects of anticoagulants on tumor development of mouse cancer cell lines B16, K1735 and CT26 in lung

Tatjana M. H. Niers, Lois W. Brüggemann, Clara P. W. Klerk, Femke J. M. Muller, Tessa Buckle, Pieter H. Reitsma, Dick J. Richel, C. Arnold Spek, Olaf Van Tellingen, Cornelis J. F. Van Noorden

Journal:

Clinical and Experimental Metastasis

Year:

2009

Language:

english

File:

PDF, 348 KB

english, 2009

26

Trabectedin (ET-743, Yondelis™) is a substrate for P-glycoprotein, but only high expression of P-glycoprotein confers the multidrug resistance phenotype

Jan-Hendrik Beumer, Tessa Buckle, Mariet Ouwehand, Niels E. F. Franke, Luis Lopez-Lazaro, Jan H. M. Schellens, Jos H. Beijnen, Olaf van Tellingen

Journal:

Investigational New Drugs

Year:

2007

Language:

english

File:

PDF, 320 KB

english, 2007

27

The effect of P-gp (Mdr1a/1b), BCRP (Bcrp1) and P-gp/BCRP inhibitors on thein vivoabsorption, distribution, metabolism and excretion of imatinib

Roos L. Oostendorp, Tessa Buckle, Jos H. Beijnen, Olaf van Tellingen, Jan H. M. Schellens

Journal:

Investigational New Drugs

Year:

2009

Language:

english

File:

PDF, 351 KB

english, 2009

28

Restricted brain penetration of the tyrosine kinase inhibitor erlotinib due to the drug transporters P-gp and BCRP

Nienke A. de Vries, Tessa Buckle, Jin Zhao, Jos H. Beijnen, Jan H. M. Schellens, Olaf van Tellingen

Journal:

Investigational New Drugs

Year:

2012

Language:

english

File:

PDF, 143 KB

english, 2012

29

The functional role of P-Glycoprotein in the blood–Brain barrier

Judith van Asperen, Ulrich Mayer, Olaf van Tellingen, Jos H. Beijnen

Journal:

Journal of Pharmaceutical Sciences

Year:

1997

Language:

english

File:

PDF, 122 KB

english, 1997

30

The Oral Route for the Administration of Cytotoxic Drugs: Strategies to Increase the Efficiency and Consistency of Drug Delivery

Heleen A. Bardelmeijer, Olaf van Tellingen, Jan H.M. Schellens, Jos H. Beijnen

Journal:

Investigational New Drugs

Year:

2000

Language:

english

File:

PDF, 113 KB

english, 2000

31

Efficacy of novel P-glycoprotein inhibitors to increase the oral uptake of paclitaxel in mice

Heleen A. Bardelmeijer, Mariët Ouwehand, Jos H. Beijnen, Jan H. M. Schellens, Olaf van Tellingen

Journal:

Investigational New Drugs

Year:

2004

Language:

english

File:

PDF, 172 KB

english, 2004

32

Bmi1 Controls Tumor Development in an Ink4a/Arf-Independent Manner in a Mouse Model for Glioma

Sophia W.M. Bruggeman, Danielle Hulsman, Ellen Tanger, Tessa Buckle, Marleen Blom, John Zevenhoven, Olaf van Tellingen, Maarten van Lohuizen

Journal:

Year:

2007

Language:

english

File:

PDF, 2.77 MB

english, 2007

33

Modulation of oral bioavailability of anticancer drugs: from mouse to man

Jan H.M Schellens, Mirte M Malingré, C.Marielle F Kruijtzer, H.A Bardelmeijer, Olaf van Tellingen, Alfred H Schinkel, Jos H Beijnen

Journal:

European Journal of Pharmaceutical Sciences

Year:

2000

Language:

english

File:

PDF, 256 KB

english, 2000

34

Concerns about anti-angiogenic treatment in patients with glioblastoma multiforme

Joost JC Verhoeff, Olaf van Tellingen, An Claes, Lukas JA Stalpers, Myra E van Linde, Dirk J Richel, William PJ Leenders, Wouter R van Furth

Journal:

Year:

2009

Language:

english

File:

PDF, 4.99 MB

english, 2009

35

Long-lasting suppression of hippocampal cell proliferation and impaired cognitive performance by methotrexate in the rat

Riejanne Seigers, Sanne B. Schagen, Wieteke Beerling, Willem Boogerd, Olaf van Tellingen, Frits S.A.M. van Dam, Jaap M. Koolhaas, Bauke Buwalda

Journal:

Behavioural Brain Research

Year:

2008

Language:

english

File:

PDF, 295 KB

english, 2008

36

Modulation of the blood–brain barrier in oncology: therapeutic opportunities for the treatment of brain tumours?

E.Marleen Kemper, Willem Boogerd, Ingrid Thuis, Jos H Beijnen, Olaf van Tellingen

Journal:

Cancer Treatment Reviews

Year:

2004

Language:

english

File:

PDF, 223 KB

english, 2004

37

Experimental models to evaluate the role of P-glycoprotein in the blood–brain tumor barrier

Olaf van Tellingen, E. Marleen Kemper, Tessa Buckle

Journal:

International Congress Series

Year:

2005

Language:

english

File:

PDF, 645 KB

english, 2005

38

High-performance liquid chromatography analysis of a novel small-molecule, anti-cancer drug, Palomid 529, in human and mouse plasma and in mouse tissue homogenates

Fan Lin, David Sherris, Jos H. Beijnen, Olaf Van Tellingen

Journal:

Journal of Chromatography B

Year:

2011

Language:

english

File:

PDF, 820 KB

english, 2011

39

Determination of NVP-BEZ235, a dual PI3K and mTOR inhibitor, in human and mouse plasma and in mouse tissue homogenates by reversed-phase high-performance liquid chromatography with fluorescence detection

Fan Lin, Gayathri Chandrasekaran, Mark C. de Gooijer, Jos H. Beijnen, Olaf van Tellingen

Journal:

Journal of Chromatography B

Year:

2012

Language:

english

File:

PDF, 829 KB

english, 2012

40

The importance of drug-transporting P-glycoproteins in toxicology

Olaf van Tellingen

Journal:

Toxicology Letters

Year:

2001

Language:

english

File:

PDF, 104 KB

english, 2001

41

THE PHARMACOLOGICAL ROLE OF P-GLYCOPROTEIN IN THE INTESTINAL EPITHELIUM

JUDITH VAN ASPEREN, OLAF H. VAN TELLINGEN, JOS H. BEIJNEN

Journal:

Pharmacological Research

Year:

1998

Language:

english

File:

PDF, 93 KB

english, 1998

42

Blood–brain barrier and chemotherapeutic treatment of brain tumors

de Vries, Nienke A, Beijnen, Jos H, Boogerd, Willem, van Tellingen, Olaf

Journal:

Expert Review of Neurotherapeutics

Year:

2006

Language:

english

File:

PDF, 134 KB

english, 2006

43

The pharmacokinetics of reduced folates after intraperltoneal and intravenous administration of racemic [6S,R]-folinic acid

Jan H. M. Sips, Olaf van Tellingen…

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1994

Language:

english

File:

PDF, 566 KB

english, 1994

44

Plasma pharmacokinetics, tissue disposition, excretion and metabolism of vinleucinol in mice as determined by high-performance liquid chromatography

Olaf van Tellingen, Anneloes L. C. Sonneveldt…

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1994

Language:

english

File:

PDF, 961 KB

english, 1994

45

Sensitive method for plasma and tumor Ko143 quantification using reversed-phase high-performance liquid chromatography and fluorescence detection

Zander, Serge A.L., Beijnen, Jos H., van Tellingen, Olaf

Journal:

Journal of Chromatography B

Year:

2013

Language:

english

File:

PDF, 805 KB

english, 2013

46

Limited Oral Bioavailability and Active Epithelial Excretion of Paclitaxel (Taxol) Caused by P-glycoprotein in the Intestine

Alex Sparreboom, Judith Van Asperen, Ulrich Mayer, Alfred H. Schinkel, Johan W. Smit, Dirk K. F. Meijer, Piet Borst, Willem J. Nooijen, Jos H. Beijnen and Olaf Van Tellingen

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 967 KB

english, 1997

47

Sildenafil is not a useful modulator of ABCB1 and ABCG2 mediated drug resistance in vivo

Lin, Fan, Hoogendijk, Lisette, Buil, Levi, Beijnen, Jos H., van Tellingen, Olaf

Journal:

European Journal of Cancer

Year:

2013

Language:

english

File:

PDF, 350 KB

english, 2013

48

Dual mTORC1 and mTORC2 inhibitor Palomid 529 penetrates the Blood-Brain Barrier without restriction by ABCB1 and ABCG2

Lin, Fan, Buil, Levi, Sherris, David, Beijnen, Jos H., van Tellingen, Olaf

Journal:

International Journal of Cancer

Year:

2013

Language:

english

File:

PDF, 675 KB

english, 2013

49

In vivo disposition of doxorubicin is affected by mouse Oatp1a/1b and human OATP1A/1B transporters

Durmus, Selvi, Naik, Jyoti, Buil, Levi, Wagenaar, Els, van Tellingen, Olaf, Schinkel, Alfred H.

Journal:

International Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 459 KB

english, 2014

50

Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin

Pang, Baoxu, Qiao, Xiaohang, Janssen, Lennert, Velds, Arno, Groothuis, Tom, Kerkhoven, Ron, Nieuwland, Marja, Ovaa, Huib, Rottenberg, Sven, van Tellingen, Olaf, Janssen, Jeroen, Huijgens, Peter, Zwart

Journal:

Nature Communications

Year:

2013

Language:

english

File:

PDF, 3.44 MB

english, 2013

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